The Methionine to Glycine Ratio

Updated: Mar 29, 2020

You have likely heard of the “methionine glycine ratio” by now, or “glycine methionine ratio” - what does this refer to? To understand the importance of balancing this ratio, we must discuss what is methylation and both methionine and glycine individually. We’ll then analyze key nutrients involved in methylation, and how you can eat to nurture methylation on an animal based diet.

Let’s start with methylation. Methyl-what?


What Is Methylation?


Methylation is a chemical process that occurs in the body involving the transfer of “methyl groups” (carbon atoms attached to hydrogen) from one substance to another.


Methylation is involved in several primary functions, including:

  • Helping to manage anxiety and depression

  • Promoting mood stability and mental flexibility

  • Contributing to detoxification of the liver

  • Helping to rid of histamines

  • Assisting in gene regulation

  • Aiding in maintenance and repair of new and existing tissues

primary functions involved in methylation
primary functions of methylation

These processes have a profound impact on our mental, physical, and emotional health.


The efficiency of the methylation process is affected by our diet and our genes to a certain extent.